A 66-year-old man with dysphagia was found to have a poorly differentiated esophageal carcinoma by incision biopsy. Following esophagectomy, reconstruction with a gastric tube was performed. Pathological examination and immunohisto-chemistry showed infiltration of adenocarcinoma cells with positive thyroid transcription factor 1-staining in the submucosal layer, which indicated metastatic esophageal carcinoma. Although no pulmonary lesion could be visualized by imaging or bronchoscopy, pulmonary origin was highly suspected as a result of positive thyroid transcription factor 1-staining. To the best of our knowledge, this is the first reported case of metastatic esophageal carcinoma from occult lung cancer (AJCC TNM stage TX).
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aDepartment of Surgery, Chutung Veterans Hospital, Hsinchu, Taipei, Taiwan, R.O.C.
bDivision of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
cNational Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
dDivision of Thoracic Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
eDepartment of Pathology, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
Correspondence to: Dr Po-Kuei Hsu and Dr Sen-Ei Shai, Department of Surgery, Chutung Veterans Hospital, 81, Section 1, Jhongfong Road, Jhudong Township, Hsinchu 310, Taiwan, R.O.C.
ABSTRACT