Journal of the Chinese Medical Association
Volume 73, Issue 5 , Pages 260-261, May 2010

Coexistence of Ankylosing Spondylitis and Systemic Lupus Erythematosus

  • Sangeeta Singh

      Affiliations

    • Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • UGC Advanced Immunodiagnostic, Training and Research Centre, Division of Immunopathology, Department of Pathology, Banaras Hindu University, Varanasi, India
    • ,
  • Gyanendra Kumar Sonkar

      Affiliations

    • Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • Division of Immunopathology and Department of Nephrology, Banaras Hindu University, Varanasi, India
    • ,
  • Usha Singh

      Affiliations

    • Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • UGC Advanced Immunodiagnostic, Training and Research Centre, Division of Immunopathology, Department of Pathology, Banaras Hindu University, Varanasi, India
    • Corresponding Author InformationCorrespondence to: Dr Usha Singh, UGC Advanced Immunodiagnostic Training and Research Centre, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Lanka, Varanasi 221005, India

Received 6 July 2009; accepted 16 April 2010.

Coexistence of ankylosing spondylitis with connective tissue diseases is uncommon. We describe here the coexistence of ankylosing spondylitis and systemic lupus erythematosus in a 35-year-old man. He presented with a 4-year history of pain in the hip joint and lower spine, and he later developed a malar rash and discoid rash. Immunological tests revealed that antinuclear antibody and double stranded DNA antibody were positive. The human leukocyte antigen B27 antigen was also found to be positive. We propose that development of systemic lupus erythematosus in this case may have been due to low grade chronic inflammation.

Key Words:  ankylosing spondylitis , antinuclear antibody , double stranded DNA antibody , human leukocyte antigen B27 , systemic lupus erythematosus

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PII: S1726-4901(10)70055-1

doi:10.1016/S1726-4901(10)70055-1

Journal of the Chinese Medical Association
Volume 73, Issue 5 , Pages 260-261, May 2010

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