Journal of the Chinese Medical Association
Volume 73, Issue 4 , Pages 208-211 , April 2010

Severe Extensive Bone Marrow Necrosis From Miliary Tuberculosis Without Granulomas and Pulmonary Presentations

  • Yun-Hsuan Lee

      Affiliations

    • Department of Medicine, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ying-Chung Hong

      Affiliations

    • Division of Hematology and Oncology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ching-Fen Yang

      Affiliations

    • Department of Pathology and Laboratory Medicine, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Hung-Ta Wu

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ling-Ju Huang

      Affiliations

    • Division of Infectious Diseases, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Cheng-Hwai Tzeng

      Affiliations

    • Division of Hematology and Oncology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Chun-Yu Liu

      Affiliations

    • Division of Infectious Diseases, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Chun-Yu Liu, Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.

Received 2 September 2009 ,Revised 28 January 2010

References 

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  2. Janssens AM , Offner FC , Van Hove WZ . Bone marrow necrosis . Cancer . 2000;88:1769–1780
  3. Paydas S, Ergin M, Baslamisli F, Yavuz S, Zorludemir S, Sahin B, et al. Bone marrow necrosis: clinicopathologic analysis of 20 cases and review of the literature . Am J Hematol . 2002;70:300–305
  4. Tang YM , Jeavons S , Stuckey S , Middleton H , Gill D . MRI features of bone marrow necrosis . AJR Am J Roentgenol . 2007;188:509–514
  5. Katzen H , Spagnolo SV . Bone marrow necrosis from miliary tuberculosis . JAMA . 1980;244:2438–2439
  6. Brastianos PK , Swanson JW , Torbenson M , Sperati J , Karakousis PC . Tuberculosis-associated haemophagocytic syndrome . Lancet Infect Dis . 2006;6:447–454
  7. Mert A, Bilir M, Tabak F, Ozaras R, Ozturk R, Senturk H, et al  Miliary tuberculosis: clinical manifestations, diagnosis and outcome in 38 adults . Respirology . 2001;6:217–224
  8. Ricci P , Bandini G , Baccarani M , Bazzocchi F , Martinelli G , Tura S . Bone marrow necrosis by diffuse metastatic intravascular obstruction . Haematologica . 1982;67:754–759
  9. Knupp C , Pekala PH , Cornelius P . Extensive bone marrow necrosis in patients with cancer and tumor necrosis factor activity in plasma . Am J Hematol . 1988;29:215–221
  10. Clarridge JE , Shawar RM , Shinnick TM , Plikaytis BB . Large-scale use of polymerase chain reaction for detection of Mycobacterium tuberculosis in a routine mycobacteriology laboratory . J Clin Microbiol . 1993;31:2049–2056
  11. Liu KT , Su WJ , Perng RP . Clinical utility of polymerase chain reaction for diagnosis of smear-negative pleural tuberculosis . J Chin Med Assoc . 2007;70:148–151
  12. Singh UB , Bhanu NV , Suresh VN , Arora J , Rana T , Seth P . Utility of polymerase chain reaction in diagnosis of tuberculosis from samples of bone marrow aspirate . Am J Trop Med Hyg . 2006;75:960–963
  13. Escobedo-Jaimes L, Cicero-Sabido R, Criales-Cortez JL, Ramirez E, Romero M, Rivero V, et al  Evaluation of the polymerase chain reaction in the diagnosis of miliary tuberculosis in bone marrow smear . Int J Tuberc Lung Dis . 2003;7:580–586
  14. Sharma SK , Mohan A , Sharma A , Mitra DK . Miliary tuberculosis: new insights into an old disease . Lancet Infect Dis . 2005;5:415–430
  15. Orme IM , Cooper AM . Cytokine/chemokine cascades in immunity to tuberculosis . Immunol Today . 1999;20:307–312
  16. Rhoades ER , Cooper AM , Orme IM . Chemokine response in mice infected with Mycobacterium tuberculosis . Infect Immun . 1995;63:3871–3877
  17. Mitsuyama M, Akagawa K, Kobayashi K, Sugawara I, Kawakami K, Yamamoto S, et al. Up-to-date understanding of tuberculosis immunity . Kekkaku . 2003;78:51–55

PII: S1726-4901(10)70043-5

doi: 10.1016/S1726-4901(10)70043-5

Journal of the Chinese Medical Association
Volume 73, Issue 4 , Pages 208-211 , April 2010

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