Journal of the Chinese Medical Association
Volume 73, Issue 3 , Pages 173-176, March 2010

Primary Small Cell Carcinoma of the Upper Urinary Tract

  • Victor Ka-Siong Kho
  • ,
  • Pei-Hui Chan

      Affiliations

    • Corresponding Author InformationCorrespondence to: Dr Pei-Hui Chan, Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, 21, Section 2, Nan-Ya South Road, Banciao, Taipei 220, Taiwan, R.O.C.

Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Banciao, Taipei, Taiwan, R.O.C.

Received 30 March 2009; accepted 8 December 2009.

Article Outline

We report a case of primary extrapulmonary small cell carcinoma of the distal ureter, with a synchronous small cell carcinoma of the ipsilateral renal pelvis. These tumors, rarely reported in the urinary tract, are locally aggressive and have a poor prognosis. A 77-year-old male bedridden patient presented with fever and chills with left side-flank pain for 3 days. Following a diagnosis of ureteral urothelial carcinoma, hand-assisted laparoscopic nephroureterectomy with bladder cuff excision was carried out. Adjuvant chemotherapy was given after pathologic report of primary small cell carcinoma of the distal ureter and a synchronous small cell carcinoma of the ipsilateral renal pelvis. After 3 cycles of combination chemotherapy, the patient died 4 months postoperatively due to sepsis.

Key Words:  extrapulmonary small cell carcinoma , hand-assisted laparoscopic nephroureterectomy , urothelial carcinoma

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PII: S1726-4901(10)70034-4

doi:10.1016/S1726-4901(10)70034-4

Journal of the Chinese Medical Association
Volume 73, Issue 3 , Pages 173-176, March 2010