Volume 73, Issue 3 , Pages 150-155, March 2010
Management of Anembryonic Pregnancy Loss: An Observational Study
Article Outline
Background
This study was undertaken to determine if expectant management with a longer waiting period is an effective and safe option for women with anembryonic pregnancy.
Methods
Women with an ultrasound diagnosis of anembryonic pregnancy were offered the option of expectant management with a 3-week waiting period or surgical evacuation according to their preference.
Results
A total of 121 women with anembryonic pregnancies participated in the study; 45 of them elected expectant management. The overall success rate was 83.3% in the expectant group and 97.3% in the surgical group. No significant complications were noted in either group.
Conclusion
Expectant management with a 3-week waiting period is an efficacious and safe option with a low risk of infection and hemorrhage. However, it is difficult to predict the exact time period before spontaneous abortion.
Key Words: abortion , anembryonic pregnancy , expectant management , uterine curettage
No full text is available. To read the body of this article, please view the PDF online.
References
- Incidence of early loss of pregnancy . N Engl J Med . 1988;319:189–194
- . Spontaneous abortions: epidemiology . In: Grudzinskas G , Chard T editor. Spontaneous Abortion: Diagnosis and Treatment . London: Springer-Verlag; 1992;p. 19–20
- . The prevalence of non-viable pregnancy at 10–13 weeks of gestation . Ultrasound Obstet Gynecol . 1996;3:170–173
- . Epidemiology of chromosomal abnormalities in spontaneous abortion: prevalence, manifestation and determinants . In: Bennett MJ , Edmonds DK editor. Spontaneous and Recurrent Abortion . Oxford: Blackwell Scientific; 1987;p. 29–50
- . Comparison of ultra-sonographic findings in spontaneous abortions with normal and abnormal karyotypes . Hum Reprod . 1997;12:823–826
- . Management of miscarriage: a randomized controlled trial of expectant management versus surgical evacuation . Hum Reprod . 2002;17:2445–2450
- . Spontaneous, threatened, and habitual abortion: their pathogenesis and treatment . N Engl J Med . 1944;230:797–806
- . Expectant management of first trimester spontaneous abortion . Lancet . 1995;345:84–86
- . Expectant management of missed miscarriage . Br J Obstet Gynaecol . 1998;105:670–671
- . Outcome of expectant management of spontaneous first trimester miscarriage: observational study . BMJ . 2002;324:873–875
- . Fetal death . Obstet Gynecol . 2007;109:153–167
- . The conservative management of early pregnancy complications: a review of the literature . Ultrasound Obstet Gynecol . 2003;22:420–430
- . Expectant, medical, or surgical treatment of spontaneous abortion in first trimester of pregnancy? A pooled quantitative literature evaluation . J Am Board Fam Prac . 1999;12:55–64
- . Early pregnancy failure—current management concepts . Obstet Gynecol Surv . 2001;56:105–113
- . Management of Early Pregnancy Failure Trial. A comparison of medical management with misoprostol and surgical management for early pregnancy failure . N Engl J Med . 2005;353:761–769
- . Serum beta-human gonadotropin levels and endometrial thickness after medical abortion . Contraception . 2001;63:255–256
- . Management of Early Pregnancy Failure Trial. Endometrial thickness after misoprostol use for early pregnancy failure . Int J Gynaecol Obstet . 2004;86:22–26
- . Sonographic characteristics of the uterine cavity following firsttrimester uterine evacuation . Ultrasound Obstet Gynecol . 2008;31:555–559
- . The quality and size of yolk sac in early pregnancy loss . Aust N Z J Obstet Gynaecol . 2006;46:413–418
PII: S1726-4901(10)70030-7
doi:10.1016/S1726-4901(10)70030-7
© 2010 Elsevier. Published by Elsevier Inc. All rights reserved.
Volume 73, Issue 3 , Pages 150-155, March 2010
