Volume 73, Issue 2 , Pages 101-103, February 2010
Invasive Adenocarcinoma of the Prostate With Urethral Tumor
Metastases of prostate cancer to the penis and urethra are rare and often represent advanced disease. We describe a case of newly diagnosed prostatic adenocarcinoma with metastases to the corpus spongiosum, cavernosum, and the anterior urethra. A male patient, 77 years of age, initially had lower urinary tract obstruction symptoms. His prostate-specific antigen level was 5.02 ng/mL. Digital rectal examination disclosed stony hard tumors at both lobes of the prostate. Transrectal ultrasound-guided biopsy of the prostate revealed adenocarcinoma over both lobes; the Gleason score was 4 + 4 = 8. Cystoscopy showed a penile urethral tumor and biopsy disclosed metastatic adenocarcinoma of the prostate; the Gleason score was 4 + 4 = 8. The patient initially received hormone therapy. Biochemical failure developed after 15 months and rapidly progressed to a hormone-refractory stage. Docetaxel was then prescribed. The patient died in the 25th month after the diagnosis.
Key Words: anterior urethra , corpus cavernosum , corpus spongiosum , metastasis , prostate cancer
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PII: S1726-4901(10)70010-1
doi:10.1016/S1726-4901(10)70010-1
© 2010 Elsevier. Published by Elsevier Inc. All rights reserved.
Volume 73, Issue 2 , Pages 101-103, February 2010
