Journal of the Chinese Medical Association
Volume 70, Issue 5 , Pages 218-221, May 2007

Fertility Preservation with Treatment of Immature Teratoma of the Ovary

  • Chia-Hui Chen

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ming-Jie Yang

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ming-Huei Cheng

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Ming-Shyen Yen

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Chiung-Ru Lai

      Affiliations

    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Peng-Hui Wang

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Peng-Hui Wang, Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.

Received 19 September 2006; accepted 26 March 2007.

Fertility preservation for a patient with advanced immature teratoma of the ovary is reported. The patient, a 29-year-old woman, delivered a healthy baby after having had ovarian immature teratoma, grade 3, uncertain stage, at 13 years of age. She was initially treated with unilateral salpingo-oophorectomy and a contralateral wedge resection for tumor invasion, followed by a 6-course cisplatin + vinblastine + bleomycin regimen, a second operation, and an additional 6-course etoposide and cisplatin regimen with complete remission. The patient delivered a healthy baby 16 years after the initial treatment. Based on this successful case, intensive fertility-preserving surgery followed by chemotherapy, even in advanced-stage immature teratomas of the ovary, may be effective in preserving the reproductive function of women with malignant immature teratomas of the ovary.

Key Words:  fertility-preserving surgery , immature teratoma , ovary

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PII: S1726-4901(09)70362-4

doi:10.1016/S1726-4901(09)70362-4

Journal of the Chinese Medical Association
Volume 70, Issue 5 , Pages 218-221, May 2007

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