Journal of the Chinese Medical Association
Volume 70, Issue 4 , Pages 176-179, April 2007

Acute Pancreatitis Associated with Ifosfamide

  • Miao-Chiu Hung

      Affiliations

    • Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
  • ,
  • Giun-Yi Hung

      Affiliations

    • Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Giun-Yi Hung, Department of Pediatrics, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.
  • ,
  • Pei-Chin Lin

      Affiliations

    • Department of Pediatrics, Kaohsiung Municipal Hsiao-Kang Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.
  • ,
  • Chui-Mei Tiu

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
  • ,
  • Yi-Ching Tien

      Affiliations

    • Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

Received 8 June 2006; accepted 31 January 2007.

Acute pancreatitis is a rare complication during chemotherapy for pediatric patients with solid tumors. We report a 9-year-old boy with osteosarcoma who experienced 2 episodes of pancreatitis 1 day and 48 days after infusion of ifosfamide (IFOS), respectively. From a MEDLINE search, this is the 3rd reported case and 2nd reported pediatric case of IFOS-induced pancreatitis, and only this case experienced late-onset pancreatitis.

Key Words:  chemotherapy , ifosfamide , pancreatitis

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PII: S1726-4901(09)70353-3

doi:10.1016/S1726-4901(09)70353-3

Journal of the Chinese Medical Association
Volume 70, Issue 4 , Pages 176-179, April 2007