Journal of the Chinese Medical Association
Volume 69, Issue 11 , Pages 549-551, November 2006

Clindamycin-induced Anaphylactic Shock During General Anesthesia

  • Chiuan-Shiou Chiou

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • ,
  • Su-Man Lin

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Shih-Pin Lin

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • ,
  • Wen-Guei Chang

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • ,
  • Kwok-Hon Chan

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Chien-Kun Ting

      Affiliations

    • Department of Anesthesiology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Chien-Kun Ting, Department of Anesthesiology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.

Received 1 March 2006; accepted 29 August 2006.

Clindamycin-related anaphylactic reaction is rarely reported. We report a male patient with buccal cancer who was undergoing radical neck dissection when life-threatening anaphylactic shock developed soon after intravenous infusion of clin-damycin. Immediate cardiopulmonary resuscitation was performed, and the patient recovered uneventfully. Perioperative anaphylactic shock is a serious problem due to the difficulty of judgment and potentially disastrous outcome. Immediate diagnosis and halting of drug infusion should be the first actions taken.

Key Words:  anaphylactic shock , clindamycin , general anesthesia

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PII: S1726-4901(09)70327-2

doi:10.1016/S1726-4901(09)70327-2

Journal of the Chinese Medical Association
Volume 69, Issue 11 , Pages 549-551, November 2006

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