Journal of the Chinese Medical Association
Volume 69, Issue 8 , Pages 372-376 , August 2006

Comparison Between F-18-FDG Positron Emission Tomography and Histology for the Assessment of Tumor Necrosis Rates in Primary Osteosarcoma

  • Teng-Le Huang

      Affiliations

    • Department of Orthopedics, China Medical University and University Hospital, Taichung, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Ren-Shyan Liu

      Affiliations

    • National Yang-Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Tain-Hsiung Chen

      Affiliations

    • National Yang-Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Winby York-Kwan Chen

      Affiliations

    • National Yang-Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Horng-Chaung Hsu

      Affiliations

    • Department of Orthopedics, China Medical University and University Hospital, Taichung, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Horng-Chaung Hsu, Department of Orthopedics, China Medical University and University Hospital, 2, Yuh-Der Road, Taichung 404, Taiwan, R.O.C.
    • ,
  • Yen-Chih Hsu

      Affiliations

    • National Yang-Ming University School of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

Received 6 January 2006 ,Accepted 6 April 2006.

References 

  1. Feltcher BD . Response of osteosarcoma and Ewing sarcoma to chemotherapy: imaging evaluation . AJR . 1991;157:825–833
  2. Sostman HD, Prescott DM, Dewhrist MW, Dodge RK, Thrall DE, Page RL, et al  MR imaging and spectroscopy for prognostic evaluation in soft tissue sarcomas . Radiology . 1994;190:269–275
  3. Murphy WA . Imaging bone tumors in the 1990's . Cancer . 1991;67:1169–1176
  4. Adler LP, Blair HF, Makley JT, Williams RP, Joyce MJ, Leisure G, et al  Noninvasive grading of musculoskeletal tumors using PET . J Nucl Med . 1991;32:1508–1512
  5. Weber G . Biochemical strategy of cancer cells and the design of chemotherapy: G.H.A. Clowes Memorial Lecture . Cancer Res . 1983;43:3466–3492
  6. Garcia JR, Kim EE, Wong FCL, Korkmaz M, Wong WH, Yang WDJ, et al. Comparison of fluorine-18-FDG PET, technetium-99m-MIBI SPECT in evaluation of musculoskeletal sarcomas . J Nucl Med . 1996;37:1476–1479
  7. Nieweg OE, Pruim J, van Ginkel RJ, Hoekstra HJ, Paans AM, Molenaar WM, et al  Fluorine-18-fluorodeoxyglucose PET imaging of soft-tissue sarcoma . J Nucl Med . 1996;37:257–261
  8. Dehdashti F, Siegel BA, Griffeth LK, Fusselman MJ, Trask DD, McGuire AH, et al. Benign versus malignant intraosseous lesions: discrimination by means of PET with 2-[18FDG] fluoro-2-deoxy-D-glucose . Radiology . 1996;200:243–247
  9. Griffeth LK, Dehdashti F, McGuire AH, McGuire DJ, Perry DJ, Moerlein SM, et al. PET evaluation of soft-tissue masses with fluoro-2-deoxy-D-glucose . Radiology . 1992;182:185–194
  10. Nieweg OE, Pruim J, Van Ginkel RJ, Hoekstra HJ, Paans AM, Molenaar WM, et al  Fluorine-18-fluorodeoxyglucose PET imaging of soft-tissue sarcoma . J Nucl Med . 1996;200:243–247
  11. Schulte M, Brecht-krauss D, Heymer B, Guhlmann A, Hartwig E, Sarkar MR, et al  Fluorodeoxyglu-cose positron emission tomography of soft tissue tumours: is a non-invasive determination of biological activity possible? . Eur J Nucl Med . 1999;26:599–605
  12. Kern KA, Brunetti A, Norton JA, Chang AE, Malawer M, Lack E, et al  Metabolic imaging of human extremity musculoskeletal tumors by PET . J Nucl Med . 1988;29:181–186
  13. Kole AC, Nieweg OE, van Ginkel RJ, Pruim J, Hoekstra HJ, Paans AM, et al  Detection of local recurrence of soft-tissue sarcoma with positron emission tomography using [18F] fluorodeoxyglucose . Ann Surg Oncol . 1997;4:57–63
  14. Link MP, Goorin AM, Miser AN, Green AA, Pratt CB, Belasco JB, et al  The effect of adjuvant chemotherapy on relapse free survival in patients with osteosarcoma of the extremity . N Engl J Med . 1986;314:1600–1606
  15. Salzer-Kuntschik M , Brand G , Delling G . Bestimmung des morphologischen Regressionsgrades nach Chemotherapie bei malignen Knochentumoren . Pathologe . 1983;4:135
  16. Salzer-Kuntschik M . Current classification of primary malignant bone tumors . Z Orthop Ihre Grenzgeb . 1992;130:257–258
  17. Meyers PA, Heller G, Healey J, Huvos A, Lane J, Marcove R, et al  Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience . J Clin Oncol . 1992;10:5–15
  18. Picci P, Rougarff BT, Bacci G, Neff JR, Sangiorgi L, Cazzola A, et al  Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities . J Clin Oncol . 1993;11:1763–1769
  19. Provisor AJ, Ettinger LJ, Nachman JB, Krailo MD, Makley JT, Yunis EJ, et al  Treatment of non-metastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group . J Clin Oncol . 1997;15:76–84
  20. Bacci G, Picci P, Ferrari S, Ruggieri P, Casadei R, Tienghi A, et al  Primary chemotherapy and delayed surgery for nonmetastatic oestosarcoma of the extremities: results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin . Cancer . 1993;72:3227–3238
  21. Haberkorn U, Strauss LG, Dimitrakopoulou A, Engenhart R, Oberdorfer F, Ostertag H, et al  PET studies of fluorodeoxyglucose metabolism in patients with recurrent col-orectal tumors receiving radiotherapy . J Nucl Med . 1991;32:1485–1490
  22. Findlay M, Young H, Cunningham D, Iveson A, Cronin B, Hickish T, et al  Noninvasive monitoring of tumor metabolism using fluorodeoxyglucose and positron emission tomography in colorectal cancer liver metastases: correlation with tumor response to fluorouracil . J Clin Oncol . 1996;14:700–708
  23. Shulkin BL, Michell DS, Ungar DR, Prakash D, Dole MG, Castle VP, et al  Neoplasms in a pediatric population: 2-(F-18)-fluoro-2-deoxy-D-glucose PET studies . Radiology . 1995;194:495–500
  24. Jones DN, McCowage GB, Sostman HD, Brizel DM, Layfield L, Charles HC, et al  Monitoring of neoadju-vant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET . J Nucl Med . 1996;37:1438–1444
  25. van Ginkel RJ, Hoekstra HJ, Pruim J, Nieweg OE, Molenaar WM, Paans AM, et al  FDG-PET to evaluate response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcoma . J Nucl Med . 1996;37:984–990
  26. Utech CI , Young CS , Winter PF . Prospective evaluation of fluorine-18 fluorodeoxyglucose positron emission tomography in breast cancer for staging of the axilla related to surgery and immunocytochemistry . Eur J Nucl Med . 1996;23:1588–1593
  27. Bender H, Kirst J, Palmedo H, Schomburg A, Wagner U, Ruhlmann J, et al. Value of 18-fluoro-deoxyglucose positron emission tomography in the staging of recurrent breast cancer . Anticancer Res . 1997;17:1687–1692

PII: S1726-4901(09)70275-8

doi: 10.1016/S1726-4901(09)70275-8

Journal of the Chinese Medical Association
Volume 69, Issue 8 , Pages 372-376 , August 2006

Article Tools