Journal of the Chinese Medical Association
Volume 69, Issue 4 , Pages 184-188, April 2006

Pyomyositis During Induction Chemotherapy for Acute Lymphoblastic Leukemia

  • Kai-Liang Kao

      Affiliations

    • Corresponding Author InformationCorrespondence to: Dr. Kai-Liang Kao, Department of Pediatrics, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.
    • ,
  • Giun-Yi Hung
    • ,
  • Betau Hwang

Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

Received 3 May 2005; accepted 25 August 2005.

Article Outline

Herein, we report on the correct diagnosis and effective treatment procedures for pyomyositis, a very rare complication that remains a diagnostic challenge in children being treated for acute lymphoblastic leukemia (ALL). We report the case of a 10-year-old girl suffering from pyomyositis with ALL. Correct diagnosis is usually delayed because the initial symptom of pyomyositis, usually local pain, is similar to the common side effect of vincristine, a drug necessary for ALL induction therapy. We summarize the procedures taken to reach a timely diagnosis and therapeutic success.

Key Words:  acute lymphoblastic leukemia , muscle abscess , pyomyositis

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Scriba J . Beitrag zun aetiologie der myositis acte . Dtsch Z Chir . 1885;22:497–502
  2. Grose C . Staphyococcal pyomyositis in South Texas . J Pediatr . 1978;93:457–458
  3. Chiedozi LC . Pyomyositis. Review of 205 cases in 112 patients . Am J Surg . 1979;137:255–259
  4. Martinez R , Garwacki J . Tropical myositis . N Engl J Med . 1971;284:196–198
  5. Echeverria P , Clay Vaughn M . Tropical pyomyositis: a diagnostic problem in temperate climates . Am J Dis Child . 1975;129:856–857
  6. Sirinavin S , McCracken GH . Primary suppurative myositis in children . Am J Dis Child . 1979;133:263–265
  7. Chaitow J , Martin HCO , Knight P , Buchanan N . Pyomysitis tropicans: a diagnostic dilemma . Med J Aust . 1980;2:512–513
  8. Gubbay AJ , Isaacs D . Pyomyositis in children . Pediatr Infect Dis J . 2000;19:1009–1013
  9. Blatt J , Reaman G , Pizzo P . Pyomyositis in acute lymphocytic leukemia heralded by cutaneous vasculitis . Med Pediatr Oncol . 1979;7:237–239
  10. Corden TE , Morgan ER . Pyomyositis during induction chemotherapy for acute lymphocytic leukemia . J Pediatr Hematol Oncol . 1996;18:323–326
  11. Bickels BJ , Ben-Sira L , Kessler A , Wientroub S . Primary pyomyositis . J Bone Joint Surg . 2002;84:2277–2286
  12. Sandler SG , Tobin W , Henderson ES . Vincristine-induced neuropathy: a clinical study of fifty leukemia patients . Neurology . 1969;19:367–374
  13. Holland JF, Scharlau C, Gailani S, Krant MJ, Olson KB, Horton J, et al  Vincristine treatment of advanced cancer: a cooperative study of 392 cases . Cancer Res . 1973;33:1258–1264
  14. Trusen A , Beissert M , Schultz G , Chittka B , Darge K . Ultrasound and MRI features of pyomyositis in children . Eur Radiol . 2003;13:1050–1055
  15. Renwick SE , Ritterbusch JF . Pyomyositis in children . J Pediatr Orthop . 1993;13:769–772

PII: S1726-4901(09)70203-5

doi:10.1016/S1726-4901(09)70203-5

Journal of the Chinese Medical Association
Volume 69, Issue 4 , Pages 184-188, April 2006

Article Tools