Journal of the Chinese Medical Association
Volume 72, Issue 4 , Pages 194-201 , April 2009

Differentiating Benign and Malignant Soft Tissue Masses by Magnetic Resonance Imaging: Role of Tissue Component Analysis

  • Chun-Ku Chen

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
  • ,
  • Hung-Ta Wu

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Hung-Ta Wu, Department of Radiology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.
  • ,
  • Hong-Jen Chiou

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
  • ,
  • Chao-Jung Wei

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
  • ,
  • Chao-Hsuan Yen

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
  • ,
  • Cheng-Yen Chang

      Affiliations

    • Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
  • ,
  • Wei-Ming Chen

      Affiliations

    • Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • Department of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.

Received 19 December 2008 ,Accepted 19 March 2009.

References 

  1. Kransdorf MJ , Murphey MD . Radiologic evaluation of soft-tissue masses: a current perspective . AJR Am J Roentgenol . 2000;175:575–587
  2. Dalinka MK , Zlatkin MB , Chao P , Kricun ME , Kressel HY . The use of magnetic resonance imaging in the evaluation of bone and soft-tissue tumors . Radiol Clin North Am . 1990;28:461–470
  3. Berquist TH , Ehman RL , King BF , Hodgman CG , Ilstrup DM . Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions . AJR Am J Roentgenol . 1990;155:1251–1255
  4. Crim JR , Seeger LL , Yao L , Chandnani V , Eckardt JJ . Diagnosis of soft-tissue masses with MR imaging: can benign masses be differentiated from malignant ones? . Radiology . 1992;185:581–586
  5. Kransdorf MJ . Magnetic resonance imaging of musculoskeletal tumors . Orthopedics . 1994;17:1003–1016
  6. Pang KK , Hughes T . MR imaging of the musculoskeletal soft tissue mass: is heterogeneity a sign of malignancy? . J Chin Med Assoc . 2003;66:655–661
  7. Sundaram M , McGuire MH , Schajowicz F . Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images . AJR Am J Roentgenol . 1987;148:1247–1250
  8. Nishimura H , Zhang Y , Ohkuma K , Uchida M , Hayabuchi N , Sun S . MR imaging of soft-tissue masses of the extraperitoneal spaces . Radiographics . 2001;21:1141–1154
  9. Hondar Wu HT , Chen W , Lee O , Chang CY . Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review . Clin Imaging . 2006;30:32–36
  10. Constable RT , Anderson AW , Zhong J , Gore JC . Factors influencing contrast in fast spin-echo MR imaging . Magn Reson Imaging . 1992;10:497–511
  11. Siegelman ES , Outwater EK . Tissue characterization in the female pelvis by means of MR imaging . Radiology . 1999;212:5–18
  12. Munk PL, Sallomi DF, Janzen DL, Lee MJ, Connell DG, O'Connell JX, et al  Malignant fibrous histiocytoma of soft tissue imaging with emphasis on MRI . J Comput Assist Tomogr . 1998;22:819–826
  13. Hashimoto N, Ueda T, Joyama S, Araki N, Beppu Y, Tatezaki S, et al  Extraskeletal mesenchymal chondrosar-coma: an imaging review of ten new patients . Skeletal Radiol . 2005;34:785–792
  14. Hermann G , Abdelwahab IF , Miller TT , Klein MJ , Lewis MM . Tumour and tumour-like conditions of the soft tissue: magnetic resonance imaging features differentiating benign from malignant masses . Br J Radiol . 1992;65:14–20
  15. Goldman SM , Davidson AJ , Neal J . Retroperitoneal and pelvic hemangiopericytomas: clinical, radiologic, and pathologic correlation . Radiology . 1988;168:13–17
  16. Pilavaki M , Chourmouzi D , Kiziridou A , Skordalaki A , Zarampoukas T , Drevelengas A . Imaging of peripheral nerve sheath tumors with pathologic correlation: pictorial review . Eur J Radiol . 2004;52:229–239
  17. Moulton JS , Blebea JS , Dunco DM , Braley SE , Bisset GS , Emery KH . MR imaging of soft-tissue masses: diagnostic efficacy and value of distinguishing between benign and malignant lesions . AJR Am J Roentgenol . 1995;164:1191–1199
  18. Beltran J , Simon DC , Katz W , Weis L . Increased MR signal intensity in skeletal muscle adjacent to malignant tumors: pathologic correlation and clinical relevance . Radiology . 1987;162:251–255
  19. Roberts CC , Liu PT , Colby TV . Encapsulated versus nonen-capsulated superficial fatty masses: a proposed MR imaging classification . AJR Am J Roentgenol . 2003;180:1419–1422
  20. Davies AM , Hall AD , Strouhal PD , Evans N , Grimer RJ . The MR imaging appearances and natural history of seromas following excision of soft tissue tumours . Eur Radiol . 2004;14:1196–1202
  21. Enzinger FM , Weiss SW . General consideration . In:  Enzinger FM ,  Weiss SW editor. Soft Tissue Tumors . St Louis: Mosby Year Book; 1995;p. 1–16
  22. Simon MA , Biermann JS . Biopsy of bone and soft-tissue lesions . J Bone Joint Surg Am . 1993;75:616–621
  23. Soler R , Castro JM , Rodriguez E . Value of MR findings in predicting the nature of the soft tissue lesions: benign, malignant or undetermined lesion? . Comput Med Imaging Graph . 1996;20:163–169
  24. Wetzel LH , Levine E . Soft-tissue tumors of the foot: value of MR imaging for specific diagnosis . AJR Am J Roentgenol . 1990;155:1025–1030
  25. Sundaram M , Sharafuddin MJ . MR imaging of benign soft-tissue masses . Magn Reson Imaging Clin N Am . 1995;3:609–627
  26. De Schepper AM , Ramon FA , Degryse HR . Magnetic resonance imaging of soft tissue tumors . J Belge Radiol . 1992;75:286–296
  27. van Rijswijk CS , Kunz P , Hogendoorn PC , Taminiau AH , Doornbos J , Bloem JL . Diffusion-weighted MRI in the characterization of soft-tissue tumors . J Magn Reson Imaging . 2002;15:302–307
  28. Benedikt RA , Jelinek JS , Kransdorf MJ , Moser RP , Berrey BH . MR imaging of soft-tissue masses: role of gadopentetate dimeglumine . J Magn Reson Imaging . 1994;4:485–490
  29. May DA , Good RB , Smith DK , Parsons TW . MR imaging of musculoskeletal tumors and tumor mimickers with intravenous gadolinium: experience with 242 patients . Skeletal Radiol . 1997;26:2–15
  30. Rosenthal RE , Wozney P . Diagnostic value of gadopentetate dimeglumine for 1.5-T MR imaging of musculoskeletal masses: comparison with unenhanced T1- and T2-weighted imaging . J Magn Reson Imaging . 1991;1:547–551
  31. van der Woude HJ , Verstraete KL , Hogendoorn PC , Taminiau AH , Hermans J , Bloem JL . Musculoskeletal tumors: does fast dynamic contrast-enhanced subtraction MR imaging contribute to the characterization? . Radiology . 1998;208:821–828

PII: S1726-4901(09)70053-X

doi: 10.1016/S1726-4901(09)70053-X

Journal of the Chinese Medical Association
Volume 72, Issue 4 , Pages 194-201 , April 2009