Volume 71, Issue 10 , Pages 532-535, October 2008
Recurrent Syncope Due to Carotid Sinus Hypersensitivity and Sick Sinus Syndrome
Article Outline
Syncope is a sudden and brief loss of consciousness with postural tone. Its recovery is usually spontaneous. There are various causes of syncope including cardiac, vascular, neurologic, metabolic and miscellaneous origins. The tracing is usually time-consuming and costly. The diagnosis of carotid sinus syncope may sometimes be difficult since the symptoms are nonspecific, especially in older persons. Here, we report the case of a 72-year-old woman who sought medical attention at our hospital due to repeated syncope episodes over the previous 5 years. Neurologic examinations showed negative results (including brain computed tomography). Twenty-four-hour ambulatory electrocardiogram monitoring showed atrial and ventricular premature contractions only. Electrophysiologic study disclosed prolonged corrected sinus node recovery time (1,737 ms) with poor atrioventricular conduction. Drop of blood pressure together with sinus bradycardia developed after left side carotid sinus massage. Both carotid sinus hypersensitivity with sick sinus syndrome contributed to this patient's syncope, and after pacemaker placement together with selective serotonin reuptake inhibitor treatment, she was free from syncope thereafter.
Key Words: hypersensitive carotid sinus syndrome , sick sinus syndrome , syncope
No full text is available. To read the body of this article, please view the PDF online.
References
- . Measurements of heart rate variability in patients with unexplained syncope . J Chin Med Assoc . 1995;56:292–297
- . The carotid sinus reflex in health and disease . Medicine . 1933;12:297–351
- . New insights into the pathophysiology of carotid sinus syndrome . Circulation . 1996;93:1411–1416
- Cost-effectiveness of dual-chamber pacing compared with ventricular pacing for sinus node dysfunction . Circulation . 2005;111:165–172
- . Midodrine in neurogenic orthostatic hypotension. A new treatment . Int Angio . 1993;12:125–131
- . Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension: a randomized, double-blind multicenter study. Midodrine Study Group . JAMA . 1997;277:1046–1051
- . Pharmacological therapy of neurally mediated syncope . Circulation . 1999;100:1242–1248
- . The use of serotonin reuptake inhibitors for the treatment of carotid sinus hypersensitivity syndrome unresponsive to dual chamber pacing . Pacing Clin Electrophysiol . 1994;17:1434–1436
- . Current trends in etiology, diagnosis, and management of neurocardiogenic syncope . Curr Opin Cardiol . 1996;11:32–41
- . Randomized comparison of atenolol and fludrocortisone acetate in the treatment of pediatric neurally mediated syncope . Am J Cardiol . 1995;76:400–402
PII: S1726-4901(08)70163-1
doi:10.1016/S1726-4901(08)70163-1
© 2008 Elsevier. Published by Elsevier Inc. All rights reserved.
Volume 71, Issue 10 , Pages 532-535, October 2008
