Journal of the Chinese Medical Association
Volume 71, Issue 5 , Pages 262-266, May 2008

Prenatal Diagnosis of Tetralogy of Fallot with Pulmonary Atresia

  • Jeng-Hsiu Hung

      Affiliations

    • Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Taipei Branch, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Jeng-Hsiu Hung, Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Taipei Branch, 289, Jianguo Road, Xindian City, Taipei 231, Taiwan, R.O.C
    • ,
  • Jen-Her Lu

      Affiliations

    • Departments of Pediatrics, National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Zen-Chung Weng

      Affiliations

    • Department of Surgery, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Chih-Yao Chen

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Kuan-Chong Chao

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Chia-Yi Selena Hung

      Affiliations

    • Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taiwan, R.O.C.
    • National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.

Received 29 June 2007; accepted 13 December 2007.

Article Outline

Tetralogy of Fallot involves an abnormal embryological development in which an unequal conotruncal division results in a small pulmonary artery and a great aortic artery. In its most severe form, the infundibulum of the right ventricle and the pulmonary artery can be atretic with the anomaly commonly referred to as pulmonary atresia with ventricular septal defect. Reported here is a case of prenatal diagnosis of tetralogy of Fallot with pulmonary atresia. The characteristic ultrasonographic findings included a small pulmonary artery, a large aorta, and a ventricular septal defect. The search for an atretic pulmonary valve and a ductus arteriosus with reversed blood flow was emphasized in the presence of asymmetrically dilated fetal heart. After birth, the newborn received single-stage total correction for the tetralogy of Fallot and was discharged a month later in stable condition. In this case report, the neonatal angiogram is added for confirming the prenatal diagnosis, which is of value in teaching fetal echocardiography to novice practitioners. We believe a prenatal diagnosis of tetralogy of Fallot can improve neonatal outcome. [J Chin Med Assoc 2008;71(5):262–266]

Key Words:  prenatal diagnosis , pulmonary atresia , tetralogy of Fallot

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References 

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PII: S1726-4901(08)70118-7

doi:10.1016/S1726-4901(08)70118-7

Journal of the Chinese Medical Association
Volume 71, Issue 5 , Pages 262-266, May 2008

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