Journal of the Chinese Medical Association
Volume 71, Issue 5 , Pages 241-246, May 2008

Coronary Computed Tomography Angiography—A Promising Imaging Modality in Diagnosing Coronary Artery Disease

  • Shu-Chen Han

      Affiliations

    • Department of Radiology, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.
    • ,
  • Ching-Chang Fang

      Affiliations

    • Cardiovascular Center, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.
    • ,
  • Yi Chen

      Affiliations

    • Cardiovascular Center, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.
    • ,
  • Chi-Liang Chen

      Affiliations

    • Cardiovascular Center, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.
    • ,
  • Shih-Pu Wang

      Affiliations

    • Cardiovascular Center, Tainan Municipal Hospital, Tainan, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Shih-Pu Wang, Cardiovascular Center, Tainan Municipal Hospital, Chong-Te Road, Tainan 670, Taiwan, R.O.C

Received 24 August 2007; accepted 19 March 2008.

Article Outline

Background

Traditionally, information on coronary artery lesions is obtained from invasive coronary angiography (CAG). The clinical applicability and diagnostic performance of the newly developed 64-slice multislice computed tomography (MSCT) scanner in coronary angiographic evaluation is not well evaluated.

Methods

Coronary computed tomography angiography (CCTA) was performed in 345 patients (119 women, 226 men; mean age, 59.64 ±11.67 years). Concomitant CAG was performed in 53 patients. The diagnostic performance of CCTA for detecting significant lesions was compared with that of CAG by 3 independent cardiologists.

Results

All CCTA was performed without complication. Comparison between CCTA and CAG was made in the 53 patients who underwent both studies. Sensitivity, specificity and the positive and negative predictive values for the 53 patients were: 81%, 99%, 87% and 99%, respectively.

Conclusion

The 64-slice MSCT, developed in recent years, allows reliable noninvasive evaluation of coronary artery morphology, including plaque, stenosis and congenital anomaly. The diagnostic accuracy of MSCT scans for detecting lesions makes it a good imaging substitute for CAG in the evaluation of these coronary segments. [J Chin Med Assoc 2008;71(5):241–246]

Key Words:  coronary artery stenosis , coronary computed tomography angiography , multislice computed tomography

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PII: S1726-4901(08)70114-X

doi:10.1016/S1726-4901(08)70114-X

Journal of the Chinese Medical Association
Volume 71, Issue 5 , Pages 241-246, May 2008

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