Journal of the Chinese Medical Association
Volume 70, Issue 8 , Pages 348-349, August 2007

Management of Anaphylactic Shock During Intravenous Fluorescein Angiography at an Outpatient Clinic

  • Chang-Sue Yang

      Affiliations

    • Departments of Ophthalmology Taipei, Taiwan, R.O.C.
    • Departments of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorrespondence to: Dr Chang-Sue Yang, Department of Ophthalmology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, R.O.C.
    • ,
  • Chun-Sung Sung

      Affiliations

    • Departments of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • Departments of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Fenq-Lih Lee

      Affiliations

    • Departments of Ophthalmology Taipei, Taiwan, R.O.C.
    • Departments of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
    • ,
  • Wen-Ming Hsu

      Affiliations

    • Departments of Ophthalmology Taipei, Taiwan, R.O.C.
    • Departments of National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.

Received 12 December 2006; accepted 23 May 2007.

Article Outline

We report the proper management of a severe adverse reaction of anaphylactic shock during intravenous fluorescein angiography at an outpatient clinic. A 72-year-old male developed the severe, life-threatening complication after intravenous injection of sodium fluorescein dye for retinal angiography. Three minutes after receiving an intravenous injection of fluorescein, the patient developed syncope, apnea and circulatory shock. Fortunately, he recovered without any neurologic sequelae after immediate intensive resuscitation with fluid and inotropic support. We highlight the occurrence of anaphylactic shock as a potentially fatal complication during intravenous fluorescein angiography. Thus, one should be alert to the possibility of this adverse event and be prepared to deal with it when fluorescein angiography is performed. When it happens, immediate intensive medical resuscitation is essential to minimize morbidity and to avoid mortality.

Key words:  anaphylactic shock , fluorescein angiography , fluorescein contrast medium

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References 

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  2. Kwiterovich KA, Maguire MG, Murphy RP, Schachat AP, Bressler NM, Bressler SB, et al. Frequency of adverse systemic reactions after fluorescein angiography: results of a prospective study . Ophthalmology . 1991;98:1139–1142
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PII: S1726-4901(08)70017-0

doi:10.1016/S1726-4901(08)70017-0

Journal of the Chinese Medical Association
Volume 70, Issue 8 , Pages 348-349, August 2007

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